•Besides C18 can have C8, C4, C3,                C2, C1 plus functionalities like              cyano (-C2H4CN), amino (-C2H4NH2),      diol (-C3H6O-CH2-CHOHCH2OH)
•Each has different polarity
•Can also do Ion Pair Chromatography or Paired-Ion Chromatography – type of RP-HPLC used to separate ionic species •Still partition chrom. but use a reagent like a quaternary ammonium salt (C4H9)4N+ to pair with analyte ions to separate by RP