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35.252 PHYSIOLOGICAL CHEMISTRY II

CREDITS                  3 credits (3 lecture hours per week)
PREREQUISITES     35.101/102      Human Anatomy and Physiology I and II
                                 35.251 Physiological Chemistry I or Permission of Instructor
CO REQUISITE        35.254 Physiological Chemistry II Lab

COURSE DESCRIPTION

This course is designed to provide a foundation in basic biochemistry for students majoring in one of the health related professions. Selected concepts in organic chemistry are integrated into this framework. Structural aspects and the properties of carbohydrates, lipids and proteins are studied. The structure and function of enzymes, their effects on reaction energetics and dynamics and the diagnostic uses of enzyme assays in clinical medicine are covered.

The chemistry of nucleic acids, protein anabolism, DNA fingerprinting and recombinant DNA technology are included. The production of biochemical energy, the common catabolic pathway and oxidative phosphorylation are studied. The biochemistry of carbohydrate, lipid and protein metabolism are detailed along with information relating nutrition to disease. Selected pathologies such as diabetes mellitus, obesity and arteriosclerosis are studied in depth.  Diagnostic tests relating to carbohydrate, lipid and protein abnormalities are included.