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36.361 CLINICAL LABORATORY INSTRUMENTATION

CREDITS                   3 credits (3 lecture hours per week)
PREREQUISITE       Junior Clinical Lab Science Standing or Permission of Instructor
CO REQUISITE         36.363 Clinical Instrumentation Labs

COURSE DESCRIPTION

This course is designed to provide an in depth knowledge of clinical chemistry laboratory instrumentation. Emphasis is placed on theoretical concepts, instrument components and design, calibration and troubleshooting of modern instrumentation and analytical methodologies in the clinical laboratory. Additionally, qualitative and quantitative applications of each instrumental technique are covered. Computer applications are included where appropriate.

The following spectroscopic instruments are studied: ultraviolet, visible and infrared absorption, fluorescence, turbidimetry and nephelometry, reflectance and atomic absorption spectroscopy. Electrochemical methods of analysis are reviewed, including: potentiometric techniques, voltammetry and coulometry. Chromatographic instrumentation and methods are discussed, such as: column and thin layer chromatography, high performance liquid chromatography, gas chromatography, ion exchange chromatography and size exclusion chromatography.