Awakenings   [1990]

Based on the book by Oliver Sacks

A new doctor finds himself with a ward full of comatose patients. He is disturbed by them and the fact that they have been comatose for decades with no hope of any cure. When he finds a possible chemical cure he gets permission to try it on one of them. This is the true story of Dr. Oliver Sacks, who brought catatonics out of their extended sleep, with Robin Williams as Sacks and DeNiro portraying one of his patients.
Watch the trailer.

Brain on Fire   [2017]

Based on Susannah Cahalan's memoir Brain on Fire: My Month of Madness

An up-and-coming journalist at the New York Post becomes plagued by voices in her head and seizures. As weeks progress and Susannah quickly moves deeper into insanity, her behaviors shift from violence to catatonia. After a series of tantrums, misdiagnoses, and a lengthy hospital stay, a doctor's last-minute intervention enables him to give her a diagnosis and a chance to rebuild her life.
Watch the trailer.

The Road Within   [2014]

A man with Tourette's syndrome brings his OCD roommate and an anorexic woman along on a road trip to bring his late mother's ashes to the ocean.
Watch the trailer.

The Intouchables   [2011]

After he becomes a quadriplegic from a paragliding accident, an aristocrat hires a young man from the projects to be his caretaker.
Watch the trailer.

My Left Foot   [1989]

Academy Awards: Best Actor, Best Actress

Christy Brown is a spastic quadriplegic born to a large, poor Irish family. His mother, Mrs Brown, recognizes the intelligence and humanity in the lad everyone else regards as a vegetable. Eventually, Christy matures into a cantankerous writer who uses his only functional limb, his left foot, to write with.
Watch the trailer.

The Soloist   [2009]

Jamie Foxx and Robert Downey, Jr.

A Los Angeles journalist befriends a homeless Juilliard-trained musician, while looking for a new article for the paper. Lopez's good intentions run headlong in the hard realities of the strength of Ayers' personal demons and the larger social injustices facing the homeless.
Watch the trailer.

Losing Chase   [1995]

A woman's clinical depression subsides when a mother's helper stands up to her abusive behavior.
Watch the trailer.

The Diving Bell and the Butterfly   [2007]

The true story of Elle editor Jean-Dominique Bauby who suffers a stroke and has to live with an almost totally paralyzed body. Although his cognitive facilities are in tact, he quickly learns that he has what is called locked-in syndrome which has resulted in him being almost completely paralyzed, including not being able to speak. One of his few functioning muscles is his left eye.
Watch the trailer.